NCT06139380

Intranasal Ketamine Effectiveness in Reducing Intramuscular Injection Pain Before Sedation Among Children

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 84 (actual)
• Sponsor: Tehran University of Medical Sciences · Academic / Other
• Sex: All
• Age: 12 Months – 7 Years
• Healthy volunteers: Not accepted

Summary

Hypothesis: Intranasal administration of ketamine would reduce the intramuscular pain of ketamine injection in children who undergo procedural sedation and analgesia in the emergency department.

Detailed description

Ketamine is a well-known medication in children's procedural sedation and analgesia. While it provides good analgesia along with sedation, its injection is painful and causes distress in children. Intranasal administration of Ketamine would reduce the intramuscular pain of ketamine injection in children who undergo procedural sedation and analgesia in the emergency department. This will also assess if intranasal administration would affect the depth of sedation and hospital length of stay of this group of patients.

Conditions

• Pain
• Intranasal Ketamine

Interventions

Type	Name	Description
DRUG	Ketamine	This is medication which is commonly used for sedation in the emergency department. At the analgesic dose, this medication can be used to reduce the pain via other routes such as intranasal.
DRUG	Sterile water	Intranasal sterile water was administered via syringe.

Timeline

• Start date: 2023-12-02
• Primary completion: 2024-04-28
• Completion: 2024-05-31
• First posted: 2023-11-18
• Last updated: 2024-06-04

Locations

1 site across 1 country: Iran