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Enrolling By InvitationNCT06138808

5-SENSE Score Validation Study

Prognostic Value of the 5-SENSE Score to Predict Focality of the Seizure-onset Zone as Assessed by Stereo-electroencephalography - a Prospective Multicenter Validation Study

Status
Enrolling By Invitation
Phase
Study type
Observational
Enrollment
400 (estimated)
Sponsor
Duke University · Academic / Other
Sex
All
Age
15 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to assess how well a new scoring system called the 5-SENSE score can predict where seizures start in the brain using Stereoelectroencephalography (SEEG). The 5-SENSE Score is a 5-point score based on routine presurgical work-up, designed to assist in predicting whether SEEG can identify a focal seizure onset zone, thereby sparing patients the risk of undergoing this invasive diagnostic procedure.

Conditions

Interventions

TypeNameDescription
OTHERStereoelectroencephalography (SEEG)Participants will under Stereoelectroencephalography (SEEG) as part of standard of care. This is not assigned by the protocol.

Timeline

Start date
2024-01-09
Primary completion
2027-01-01
Completion
2027-06-01
First posted
2023-11-18
Last updated
2026-02-13

Locations

19 sites across 12 countries: United States, Australia, Austria, Canada, Czechia, Denmark, France, Germany, Japan, Romania, Spain, Switzerland

Source: ClinicalTrials.gov record NCT06138808. Inclusion in this directory is not an endorsement.