NCT06138106

Developing a Nutritional Supplement to Increase Collagen Synthesis in People

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (estimated)
• Sponsor: University of California, Davis · Academic / Other
• Sex: All
• Age: 18 Years – 30 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to test whether a natural product supplement can potentiate the increase in collagen synthesis following the ingestion of collagen protein. The investigators have developed a model of natural (GRAS certified) products that stimulate collagen synthesis, in vitro. The investigators will determine whether the natural product supplement can potentiate the collagen synthetic response to the ingestion of collagen protein. Basal and fed serum will be isolated and these samples will be used to treat human engineered ligaments.

Conditions

• Dietary Supplements
• Connective Tissue
• Exercise

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Natural Product Supplement	Participants will have blood drawn before and one hour after consuming the natural product supplement. For 7-days the participants will perform load-bearing exercise and consume the supplement. On the final day, blood will be collected 4 hours after the final exercise bout.
DIETARY_SUPPLEMENT	Placebo control	Participants will have blood drawn before and one hour after consuming the placebo supplement. For 7-days the participants will perform load-bearing exercise and consume the supplement. On the final day, blood will be collected 4 hours after the final exercise bout.

Timeline

• Start date: 2023-11-21
• Primary completion: 2026-06-01
• Completion: 2026-06-01
• First posted: 2023-11-18
• Last updated: 2026-01-30

Locations

1 site across 1 country: United States