NCT06136455

A Study to Investigate Salivary Flow and Potential of Hydrogen (pH) Following Use of Essential-Oil Containing Mouthwashes

A Randomized Clinical Trial to Investigate Salivary Flow and pH Following Use of Essential-Oil Containing Mouthwashes

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 164 (actual)
• Sponsor: Johnson & Johnson Consumer Inc. (J&JCI) · Industry
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The purpose of this trial is to evaluate the amount of saliva generated and changes in the oral Potential of Hydrogen (pH) after a single use of essential oil (EO)-containing mouth rinses compared to a negative control. Three EO mouthwash formulations will be investigated in this regard, with the negative control being tap water.

Conditions

• Healthy

Interventions

Type	Name	Description
DRUG	Listerine Clinical Solutions Teeth Strength	After brushing for 1 timed minute, participants will rinse full strength for 1 minute with Listerine Clinical Solutions Teeth Strength mouthwash.
DRUG	Listerine Total Care Zero Alcohol Mouthwash	After brushing for 1 timed minute, participants will rinse full strength for 1 minute with Listerine Total Care Zero mouthwash.
OTHER	Listerine Cool Mint Zero Alcohol Mouthwash	After brushing for 1 timed minute, participants will rinse full strength for 30 seconds with Listerine Cool Mint Zero mouthwash.
DRUG	Colgate Cavity Protection Toothpaste	Participants will brush for 1 timed minute with Colgate Cavity Protection toothpaste.

Timeline

• Start date: 2023-11-13
• Primary completion: 2023-11-16
• Completion: 2023-11-16
• First posted: 2023-11-18
• Last updated: 2024-01-03

Locations

1 site across 1 country: United States