NCT06134700

Low Pressure Versus Standard Pressure Pneumoperitoneum in Laparoscopic Nephrectomy

Low Pressure Versus Standard Pressure Pneumoperitoneum in Laparoscopic Nephrectomy: A Prospective Randomised Controlled Trial

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 44 (estimated)
• Sponsor: Institute of medicine, Maharagjung medical campus · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Laparoscopic nephrectomies are commonly performed these days and are considered gold standard for both benign and malignant diseases as well as for donor nephrectomies. Despite being a widely performed surgery worldwide still there are areas of uncertainties due to lack of evidences. One of such area of dilemma is the optimum pressure of pneumoperitoneum. This study aims to identify if lower pressure of pneumoperitoneum is safe during laparoscopic nephrectomies. This is a hospital based prospective randomized control study. All the patients undergoing laparoscopic nephrectomies at department of urology and kidney transplant surgery will be eligible for study. Patients will be divided into low pressure or standard pressure pneumoperitoneum by simple random sampling and comparison of various intraoperative and post-operative parameters will be done to assess the safety of low pressure pneumoperitoneum

Conditions

• Non-Functioning Kidney
• Renal Cell Carcinoma

Interventions

Type	Name	Description
PROCEDURE	Laparoscopic Surgery	* Surgery will then proceed at either 8 - 10 or 12 - 15 mmHg pneumoperitoneum pressure depending on study group the patient falls into * Port Placement * Reflection of colon * Isolation of ureterogonadal packet * Upper pole dissection * Hilar dissection * Vessel clipping and division * Dissection of kidney * Delivery through either Pfannenstiel or iliac fossa incision

Timeline

• Start date: 2023-11-15
• Primary completion: 2024-08-15
• Completion: 2024-12-15
• First posted: 2023-11-18
• Last updated: 2023-11-18