NCT06133816

Lung Cancer Screening Eligibility Assessment

Using a Simplified Tool to Predict Lung Cancer Screening (LCS) Eligibility: Experiment to Test Effects of Messaging on Response Rates

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 6,125 (actual)
• Sponsor: Abramson Cancer Center at Penn Medicine · Academic / Other
• Sex: All
• Age: 50 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

The primary purpose of this study evaluate if different messaging impacts response rates to a brief survey (i.e., the simplified eligibility tool) that is designed to estimate pack-year eligibility for lung cancer screening (LCS). This will help inform the best way to increase response rates to the tool in future intervention studies designed to increase LCS, and expand upon survey methodology in general.

Detailed description

Despite growing evidence that lung cancer screening (LCS) reduces lung cancer-specific mortality, LCS across the United States is remarkably low. This is due in part to challenges with identifying adults who meet eligibility criteria for lifetime smoking intensity (i.e., 20 pack-years or greater), which is often missing from the electronic medical record. We have developed a simplified eligibility tool that has shown accuracy in estimating pack-years. But given the potential for low response rates, there is a great need to identify effective strategies to increasing response rates equitably prior to using it in practice or in future studies. The primary purpose of this study evaluate if different messaging impacts response rates to a brief survey (i.e., the simplified eligibility tool) that is designed to estimate pack-year eligibility for lung cancer screening (LCS). This will help to identify the best way to increase response rates to the tool in future intervention studies designed to increase LCS, and expand upon survey methodology in general.

Conditions

• Lung Cancer

Interventions

Type	Name	Description
BEHAVIORAL	Framed Introductory Message A	Randomly assign patients to receive introductory message encouraging them to complete the survey (version A).
BEHAVIORAL	Framed Introductory Message B	Randomly assign patients to receive introductory message encouraging them to complete the survey (version B).
BEHAVIORAL	Framed Introductory Message C	Randomly assign patients to receive introductory message encouraging them to complete the survey (version C).
BEHAVIORAL	Framed Tobacco Use Message A	Randomly assign patients to receive norming message related to tobacco use (version A).
BEHAVIORAL	Framed Tobacco Use Message B	Randomly assign patients to receive norming message related to tobacco use (version B).
BEHAVIORAL	Financial Incentive	Randomly assigned patients to be entered into a drawing to receive a $100 gift card.

Timeline

• Start date: 2023-07-31
• Primary completion: 2024-01-31
• Completion: 2024-01-31
• First posted: 2023-11-18
• Last updated: 2025-05-31
• Results posted: 2025-05-31

Locations

1 site across 1 country: United States