NCT06132997

Medical Thoracoscopy in Treatment Outcomes of Empyema Management

Medical Thoracoscopy Versus Conventional Intercostal Tube in Treatment Outcomes of Empyema Management

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: Hend Mohamed Sayed Mohamed · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

To evaluate the efficacy of drainage achieved by thoracoscopy vs tube drainage alone. To compare clinical outcomes such as length of hospital stay, need for additional procedures, and treatment failure rates between the two drainage methods. To asses resolution of pleural infection and rates of fluid re-accumulation over follow-up. To compare safety profiles and complication rates of thoracoscopy versus tube drainage alone

Detailed description

Empyema is a serious infection characterized by pus accumulation in the pleural space. Effective drainage and treatment is necessary for resolution. Traditionally, intercostal tube placement was standard initial management. However, recent studies have compared outcomes of early medical thoracoscopy or video-assisted thoracoscopic surgery (VATS). Thoracoscopy enables direct visualization for thorough pleural space cleansing and debridement under direct vision. medical thoracoscopy significantly improved drainage adequacy and reduced treatment failure risks compared to tube drainage alone. Also reported shorter hospital stays and lower complication rates with early thoracoscopy-directed management. Additional benefits of thoracoscopy include enabling talc pleurodesis for reducing empyema recurrence. thoracoscopy-directed pleurodesis achieved higher long-term success rates than tube drainage followed by pleurodesis. Overall, current evidence indicates medical thoracoscopy provides superior empyema treatment outcomes to conventional tube drainage through optimized drainage and debridement under direct visualization.

Conditions

• Empyema

Interventions

Type	Name	Description
PROCEDURE	Thoracoscopy procedure	is a minimally invasive endoscopic procedure utilized by pulmonologists to evaluate, diagnose, and treat pleural pathologies of the lung, mainly pleural effusions.
PROCEDURE	Chest tube thoracostomy	Insert chest intercostal tube without thoracoscopy

Timeline

• Start date: 2023-12-24
• Primary completion: 2024-12-28
• Completion: 2025-03-24
• First posted: 2023-11-15
• Last updated: 2023-11-15