NCT06129136

The Effect of Nature-based Exposure on the Immune System and Skin Health of Atopic Dermatitis Patients.

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 142 (actual)
• Sponsor: Uute Scientific Oy · Industry
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The purpose of the study is to explore the effect of nature-based exposure on immunological biomarkers and the condition and symptoms of atopic skin. Our hypothesis is that regular exposure to nature-based, high biodiversity material on skin, strengthens the skin's protective barrier and has a positive effect on the immunological biomarkers associated with atopic dermatitis. Further our hypothesis is that the difference between the groups (active and placebo) is noticeable during winter time when the disease is typically worse because of the cold weather. The study aim at scientific publication and is double-blinded and placebo-controlled. Time of the intervention is 6-7 months: intervention starts before the Finnish winter time and ends before the summer.

Conditions

• Atopic Dermatitis

Interventions

Type	Name	Description
OTHER	Nature-based exposure by biodiversity component in lotion.	Lotion is used at minimum three times per week and at least to arms. No restrictions to normal life and self-care. Atopy medicines and lotions are allowed when needed, only the usage amount is followed.
OTHER	Placebo group using colored lotion.	Lotion is used at minimum three times per week and at least to arms. No restrictions to normal life and self-care. Atopy medicines and lotions are allowed when needed, only the usage amount is followed.

Timeline

• Start date: 2023-08-17
• Primary completion: 2024-06-17
• Completion: 2024-12-31
• First posted: 2023-11-13
• Last updated: 2025-04-04

Locations

1 site across 1 country: Finland