Trials / Active Not Recruiting
Active Not RecruitingNCT06126341
A Study to Identify Barriers to Cellular Therapies for People With Plasma Cell Disorders
Prospective Multi-Center Study to Identify Barriers to Cellular Therapies in Patients With Plasma Cell Disorders PROACT PCD
- Status
- Active Not Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 49 (actual)
- Sponsor
- Memorial Sloan Kettering Cancer Center · Academic / Other
- Sex
- All
- Age
- 18 Years – 80 Years
- Healthy volunteers
- Not accepted
Summary
This is an observational study that will include both participants with relapsed/refractory Multiple Myeloma and their doctors. The purpose of this study is to gather information about the use of hematopoietic cell transplantation/HCT and B-cell maturation antigen /BCMS targeted chimeric antigen receptor/CAR autologous T-cell therapy.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Lecture on the role of cellular therapies in relapse/refractory multiple myeloma/RRMM | Physician investigators will review a lecture on the role of cellular therapies in relapse/refractory multiple myeloma/RRMM that discusses current information in regards to available cellular therapies in RRMM and a proposed treatment algorithm. |
| BEHAVIORAL | Hospital Anxiety and Depression Scale | Depression and anxiety will be assessed using the Hospital Anxiety and Depression Scale (HADS), a 14-item self-rated questionnaire |
| BEHAVIORAL | Duke-UNC Functional Social Support Questionnaire | A 14-item, self-administered, multidimensional, functional social support questionnaire has been reduced to an 11 items to a brief and easy-to-complete two-scale, eight-item functional social support instrument. |
| BEHAVIORAL | Distress Thermometer | The Distress Thermometer is a single-item visual analog scale used to screen cancer patients for the presence of psychological distress |
| BEHAVIORAL | FACT-BMT | The FACT-BMT Version 4.0 is a 37 item self-report questionnaire that measures the effect of cancer on Quality of Life domains |
| BEHAVIORAL | Psychosocial Assessments of Candidates for Transplantation | The PACT scale is a single page 10-item rating scale with high inter-rater reliability that has been used extensively in solid organ transplantation |
Timeline
- Start date
- 2023-11-03
- Primary completion
- 2029-05-03
- Completion
- 2029-05-03
- First posted
- 2023-11-13
- Last updated
- 2026-02-19
Locations
8 sites across 1 country: United States
Source: ClinicalTrials.gov record NCT06126341. Inclusion in this directory is not an endorsement.