NCT06125340

Optimizing Care for Children Hospitalized With Community-acquired Pneumonia: Short-course Therapy

Optimizing Care for Children Hospitalized With Community-acquired Pneumonia: a Feasibility Randomized Controlled Trial of Short-course Antibiotic Therapy

• Status: Recruiting
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 75 (estimated)
• Sponsor: Jeffrey · Academic / Other
• Sex: All
• Age: 6 Months – 18 Years
• Healthy volunteers: Not accepted

Summary

Children are commonly hospitalized because of community-acquired pneumonia (CAP). There are multiple high-quality randomized trials of short-course antibiotic therapy (3-5 days of treatment) for adults hospitalized with CAP - but there is very little evidence in children. We intend to do a pilot RCT of short-course (3-5 days) vs standard-duration (8-10 days) antibiotic therapy for children hospitalized for CAP.

Conditions

• Community-acquired Pneumonia

Interventions

Type	Name	Description
DRUG	Placebo	5 days of placebo to be given after 3-5 days of antibiotics
DRUG	Amoxicillin	Standard-dose amoxicillin (approved by Health Canada) to be given x 5 days.

Timeline

• Start date: 2024-04-17
• Primary completion: 2025-11-30
• Completion: 2026-01-01
• First posted: 2023-11-09
• Last updated: 2024-12-12

Locations

1 site across 1 country: Canada