NCT06125210

Application of Early Bundle Management of Mechanical Ventilation to Prevent Ventilator Dependence in Children

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 150 (estimated)
• Sponsor: Children's Hospital of Fudan University · Academic / Other
• Sex: All
• Age: 28 Days – 18 Years
• Healthy volunteers: Not accepted

Summary

This study is based on the risk factors of previous studies to formulate a bundle treatment plan to prevent ventilator dependence in children, in order to reduce the proportion of ventilator dependence in children and provide a theoretical basis for reasonable intervention of children with mechanical ventilation. Participants will receive intensive rehabilitation, nutrition, and tracheotomy at different time periods. Researchers will compare the control group to see whether it can reduce the incidence of ventilator dependence

Conditions

• Prolonged Mechanical Ventilation

Interventions

Type	Name	Description
BEHAVIORAL	early bedside rehabilitation	① electrical diaphragm stimulation, ② electrical muscle stimulation, ③ passive limb movement, ④ respiratory rehabilitation.
DIETARY_SUPPLEMENT	nutrition program	(1) nutrition department consultation, (2) MDT to develop individualized nutritional pathways, nutrient formulations and use methods, and achieve the target nutritional level within 2 weeks
PROCEDURE	tracheotomy	early tracheotomy for special diseases (e.g central nervous system diseases) receiving mechanical ventilation 14-21 days recommended tracheotomy

Timeline

• Start date: 2024-09-01
• Primary completion: 2026-12-31
• Completion: 2026-12-31
• First posted: 2023-11-09
• Last updated: 2026-02-17

Locations

1 site across 1 country: China