NCT06122675

Cerebellar Deep Brain Stimulation for Movement Disorders in Cerebral Palsy in Children and Young Adults

Cerebellar Deep Brain Stimulation for Severe Combined Movement Disorders and Spasticity in Children and Young Adults with Cerebral Palsy

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 10 (estimated)
• Sponsor: University of California, San Francisco · Academic / Other
• Sex: All
• Age: 7 Years – 25 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to test the safety of placing Deep Brain Stimulators (DBS) in a part of the brain called the cerebellum and using electrical stimulation of that part of the brain to treat movement symptoms related to cerebral palsy. Ten children and young adults with dyskinetic cerebral palsy will be implanted with a Medtronic Percept Primary Cell Neurostimulator. We will pilot videotaped automated movement recognition techniques and formal gait analysis, as well as collect and characterize each subject's physiological and neuroimaging markers that may predict hyperkinetic pathological states and their response to therapeutic DBS.

Conditions

• Dyskinetic Cerebral Palsy
• Dystonic Cerebral Palsy

Interventions

Type	Name	Description
DEVICE	DBS	Implanted in the cerebellum.

Timeline

• Start date: 2024-03-26
• Primary completion: 2029-01-01
• Completion: 2029-03-31
• First posted: 2023-11-08
• Last updated: 2025-03-27

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated device study