NCT06119009

New-onset Heart Blocks After Noncardiac Surgery: a Retrospective Study of More Than 280,000 Patients

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 281,497 (actual)
• Sponsor: Chinese PLA General Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study aimed to investigate new-onset heart blocks after noncardiac surgery, identify risk factors, and develop a prediction model.

Detailed description

Objective: This study aimed to investigate new-onset heart blocks after noncardiac surgery, identify risk factors, and develop a prediction model. Methods: A retrospective cohort study included 281,497 patients aged 18 or older who underwent noncardiac surgery at a single center between Jan 2008 and Aug 2019. The main outcome was postoperative new-onset heart blocks within one year, including atrioventricular and bundle blocks. Prognostic impact was assessed using Kaplan-Meier survival curves and time-dependent Cox regression analysis. Perioperative data was used for machine learning models (logistic regression, support vector machine, random forest, decision tree). Model performance was measured using the area under the receiver operating characteristic curve (AUC).

Conditions

• Heart Block
• Risk Factor

Interventions

Type	Name	Description
OTHER	non interventions

Timeline

• Start date: 2008-01-01
• Primary completion: 2019-08-01
• Completion: 2019-08-01
• First posted: 2023-11-07
• Last updated: 2023-11-07