Clinical Trials Directory

Trials / Unknown

UnknownNCT06118398

Efgartigimod in Acute Neuromyelitis Optica Spectrum Disorders

Effectiveness and Safety of Efgartigimod in the Acute Phase of Neuromyelitis Optica Spectrum Disorders-a Multicentric, Controlled, Retrospective, Real-Word Study

Status
Unknown
Phase
Study type
Observational
Enrollment
24 (estimated)
Sponsor
Feng Jinzhou · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This study aims to retrospective investigate the safety and effectiveness of Efgartigimod in the acute phase of neuromyelitis optica spectrum disorders (NMOSD) patients.

Detailed description

This is a multicentre, controlled, retrospective, real-world study which aims to compare the safety and effectiveness of Intravenous methylprednisolone (IVMP) with Efgartigimod injection add-on treatment with IVMP treatment in acute NMOSD patients. Twenty-four patients from 6 centres in China will be enrolled.

Conditions

Interventions

TypeNameDescription
DRUGIntravenous methylprednisolone (IVMP) and EfgartigimodIVMP 800-1000mg/day for 3-5 days plus Efgartigimod (Efgartigimod: 10mg/kg IV on Day 1, Day 8, Day 15 and Day 22 after IVMP.)
DRUGIVMPIVMP 800-1000mg/day for 3-5 days.

Timeline

Start date
2023-11-05
Primary completion
2024-11-05
Completion
2025-05-05
First posted
2023-11-07
Last updated
2023-11-07

Source: ClinicalTrials.gov record NCT06118398. Inclusion in this directory is not an endorsement.