NCT06115707

Head Position After Endovascular Therapy

Head Positioning After Endovascular Therapy for Acute Ischemic Stroke: A Randomized Controlled Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 1,368 (actual)
• Sponsor: Zhengzhou Yuan · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The aim of this trial is to investigate whether head elevation position after endovascular treatment can improve the 90-day functional outcome of acute large vessel occlusion in the anterior circulation.

Detailed description

The optimal head position for patients with acute ischemic stroke (AIS) remains uncertain. The HeadPoS study revealed that there is no significant difference in disability outcomes between patients who are placed in a lying-flat position for 24 hours and those who are placed in a sitting-up position with the head elevated to at least 30 degrees for 24 hours. However, this study included both patients with ischemic and hemorrhagic strokes, and most of the patients had mild strokes (median National Institutes of Health Stroke Scale score of 4). It is unclear how to arrange the patient's head position after endovascular treatment. The hypothesis of this trial: Compared with the lying flat head positioni, the head elevation position after endovascular treatment can significantly improve the 90-day functional outcome of acute large vessel occlusion in the anterior circulation.

Conditions

• Stroke, Acute
• Endovascular Therapy

Interventions

Type	Name	Description
OTHER	The lying flat (0°-10°) head position for 72 hours	The lying flat (0°-10°) head position for 72 hours after endovascular therapy.
OTHER	The The head elevation (30°-40°) position for 72 hours	The head elevoatin (30°-40°) position for 72 hours after endovascular therapy.

Timeline

• Start date: 2023-11-13
• Primary completion: 2025-04-26
• Completion: 2025-04-26
• First posted: 2023-11-03
• Last updated: 2025-11-28

Locations

67 sites across 1 country: China