Trials / Unknown
UnknownNCT06115655
A Single-center, Prospective Cohort Study on the Differentiation of Benign and Malignant Bile Duct Stenosis Based on Bile and Peripheral Blood cfDNA Methylation Profiles
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 161 (estimated)
- Sponsor
- Air Force Military Medical University, China · Academic / Other
- Sex
- All
- Age
- 18 Years – 90 Years
- Healthy volunteers
- Accepted
Summary
The goal of this observational study is to detect the methylation characteristics of cfDNA in the bile and plasma of patients with bile duct stricture. The main question it aims to answer is: Can the developed model, using peripheral blood and bile cell-free DNA sequencing, work well in screening and classifying unknown biliary stricture? Participants will collect approximately 10ml of peripheral blood and 5ml of bile from the patient.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIAGNOSTIC_TEST | cfDNA methylation detection | Extract cfDNA from bile and plasma, and perform methylation detection. |
Timeline
- Start date
- 2023-10-01
- Primary completion
- 2024-10-01
- Completion
- 2024-10-30
- First posted
- 2023-11-03
- Last updated
- 2023-11-03
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT06115655. Inclusion in this directory is not an endorsement.