NCT06114706

Best Assessment of Sore Throat and Antibiotic Prescribing

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 450 (estimated)
• Sponsor: Vastra Gotaland Region · Other Government
• Sex: All
• Age: 6 Years
• Healthy volunteers: Not accepted

Summary

This project aims to investigate if an organisational change of patient flow away from medical practitioners can reduce unnecessary antibiotic prescribing in patients attending with a sore throat as the main complaint.

Detailed description

Today patients appear either at a PHC centre or at the Pharmacy. The Pharmacy may provide advice on analgesic or refer the patient to a PHC centre. At the PHC centre, the patient may first appear to the medical practitioner or a nurse pending on local routines. The current Swedish guideline recommends no antibiotics and no testing for patients with 0-2 Centor criteria. For patients with 3-4 Centor criteria the guideline recommends testing and only consider antibiotics if GAS is present. COVID-19 has gradually transformed from expressing itself as a severe lower respiratory tract infection to be more of an upper respiratory tract infection. Furthermore, COVID-19 is likely to transform from a pandemic to an endemic state with a low continuous incidence. Hence, in response to COVID-19 it seems crucial to identify to what extent the common sore throat is caused by the SARS-CoV-2. Furthermore, a large controlled clinical trial is required to sort out if patients attending with a sore throat as the main complaint are best managed by medical practitioners, nurses or pharmacists. This study aims to perform such a controlled clinical trial comparing the outcome of sore throat patients management by medical practitioner, nurses and pharmacists. This study also aims to investigate to what extent the SARS-CoV-2 virus is identified in these patients.

Conditions

• Pharyngitis

Interventions

Type	Name	Description
BEHAVIORAL	Physicians assess patients	Physicians are asked to assess patients following the current Swedish guideline
BEHAVIORAL	Nurses assess patients	Nurses are asked to assess patients following the current Swedish guideline
BEHAVIORAL	Pharmacists assess patients	Pharmacists are asked to assess patients following the current Swedish guideline

Timeline

• Start date: 2024-03-04
• Primary completion: 2027-06-30
• Completion: 2027-06-30
• First posted: 2023-11-02
• Last updated: 2026-03-16

Locations

4 sites across 1 country: Sweden