NCT06114121

Intrathecal Morphine vs. Intrathecal Morphine and Regional Anesthesia After Cesarean Section.

Comparing Intrathecal Morphine and Erector Spinae Plane Regional Anesthesia Against Intrathecal Morphine Alone for Post-Cesarean Section Pain

• Status: Withdrawn
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: University of Miami · Academic / Other
• Sex: Female
• Age: 18 Years – 45 Years
• Healthy volunteers: Not accepted

Summary

The objective of the study is to optimize post-operative analgesia and improve patient satisfaction while reducing total opioid consumption after cesarean section

Conditions

• Post-operative Pain

Interventions

Type	Name	Description
PROCEDURE	erector spinae plane block (ESP)	nerve block for abdominal pain. administered once immediately prior to spinal anesthetic standard of care.
DRUG	Duramorph	100 micrograms (mcg) of morphine administered in the spinal medications one time.
DRUG	Ropivacaine	Ropivacaine 0.5% between 20-40 milliliters will be administered once in the ESP block (in the spine) depending on patient weight to keep under the maximum dose.
DRUG	Bupivacaine Injection	Bupivacaine 0.75% 1.4-1.7 milliliters (10-12 milligrams) spinal medication. administered one time.

Timeline

• Start date: 2024-07-10
• Primary completion: 2024-09-10
• Completion: 2024-09-10
• First posted: 2023-11-02
• Last updated: 2024-09-19

Regulatory

• FDA-regulated drug study