NCT06107556

Agonist and Antagonist Muscle Activations in the Lower Limbs During Walking After Central Nervous System Injury

Neuromechanical Characterization of Agonist and Antagonist Muscle Activations in the Lower Limbs During Walking After Central Nervous System Injury

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 100 (estimated)
• Sponsor: Henri Mondor University Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The retrospective study investigates the part of responsibility of neuromuscular disorders associated with chronic hemiparesis in walking impairment.

Detailed description

After injury to the central nervous system, walking disorders are associated with complex neuromuscular mechanisms that alter the direction and intensity of the descending control, reflex reactions to kinematic changes and the mechanical components of soft tissues. The dissociated analysis of these mechanisms and their interactions during multi-segmental movements and especially during walking is poorly described. However, a quantified assessment of the responsibility of each of the neuromuscular mechanisms in the functional disorder would guide the choice of treatments. 3D gait laboratories provide kinematic data from synchronized walking to surface electromyograms as part of additional assessments to assist in the follow-up of patients with chronic hemiparesis. Retrospective analysis of these data would help to better characterize muscular activation disorders and passive resistance to movement during walking in this population.

Conditions

• Stroke
• Walking, Difficulty
• Spasticity/Paresis

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Gait analysis	3D gait analysis with electromyographic measurements

Timeline

• Start date: 2023-10-19
• Primary completion: 2023-10-19
• Completion: 2024-06-30
• First posted: 2023-10-30
• Last updated: 2023-10-30

Locations

1 site across 1 country: France