NCT06105476

Effect of Protein and Retinol on Alcohol-induced FGF21

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 31 (actual)
• Sponsor: University of Copenhagen · Academic / Other
• Sex: All
• Age: 18 Years – 50 Years
• Healthy volunteers: Accepted

Summary

The aims of this study are two-fold. First to investigate the influence of protein on the FGF21 response induced by alcohol, and second to investigate the influence of retinol on FGF21 concentrations and the FGF21 response induced by alcohol. Exploratory, and in order to investigate mechanisms behind the potential influence on alcohol-induced FGF21 response from protein or retinol intake, plasma glucose, insulin, glucagon, ethanol, acetaldehyde, acetate, retinol, retinoic acid, as well as subjective rating of appetite, will be measured.

Conditions

• Healthy

Interventions

Type	Name	Description
OTHER	Alcohol	Test drink with 12 g alcohol (30 g vodka 40%) in water
OTHER	Alcohol+protein	Test drink with 12 g alcohol (30 g vodka 40%) and 25 g whey protein in water
OTHER	Alcohol+retinol	Test drink with 12 g alcohol (30 g vodka 40%) and 1000 μg retinol in water
OTHER	Retinol	Test drink with 1000 μg retinol in water

Timeline

• Start date: 2023-11-20
• Primary completion: 2024-03-31
• Completion: 2024-03-31
• First posted: 2023-10-27
• Last updated: 2024-08-27

Locations

1 site across 1 country: Denmark