Clinical Trials Directory

Trials / Recruiting

RecruitingNCT06105411

Siderophore-labelled Positron Emission Tomography for Correlating Invasive Fungal InfeCtions

Status
Recruiting
Phase
Study type
Observational
Enrollment
10 (estimated)
Sponsor
Peter MacCallum Cancer Centre, Australia · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This trial will demonstrate localised uptake of a radiolabelled fungal component (siderophore) in areas of known specific invasive fungal (Aspergillus) infection.

Detailed description

This open label, single centre, proof of concept pilot imaging trial will evaluate technique for the diagnosis of invasive Aspergillus infection. It aims to demonstrate uptake of the gallium-siderophore tracer at sites of known proven/probable invasive aspergillus app infection. It will also assess the safety and tolerability of this technique. 10 patients within 2 weeks of proven or probable invasive fungal infection (IFI) diagnosis will be recruited to this study over a period of 12-24 months.

Conditions

Interventions

TypeNameDescription
DIAGNOSTIC_TEST68Ga-labelled TAFC PET/CT scan68Ga-labelled TAFC PET/CT scan (whole body)

Timeline

Start date
2023-12-01
Primary completion
2026-10-01
Completion
2027-04-01
First posted
2023-10-27
Last updated
2025-09-05

Locations

1 site across 1 country: Australia

Source: ClinicalTrials.gov record NCT06105411. Inclusion in this directory is not an endorsement.