Trials / Recruiting
RecruitingNCT06105242
Biological Sex and CTEPH-related RV Dysfunction and Recovery (BIOSPHeRe)
Biological Sex and Sex Hormones Moderate Right Ventricular (RV) Dysfunction and Recovery in Chronic Thromboembolic Pulmonary Hypertension
- Status
- Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 10 (estimated)
- Sponsor
- Intermountain Health Care, Inc. · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
1. To identify biological sex differences in baseline RV function in CTEPH 2. To identify biological sex differences in recovery of RV function after PTE surgery in CTEPH 3. To determine if sex hormone levels relate to RV function at CTEPH diagnosis and during recovery after PTE.
Detailed description
Aims 1 and 2 together comprise a retrospective cohort study. We will identify historical subjects with newly diagnosed CTEPH using a clinical database. We will perform TTE strain analysis (RVGLS) to compare RV function between the biologic sexes at diagnosis and after surgical correction of CTEPH (to assess recovery).
Conditions
Timeline
- Start date
- 2022-05-30
- Primary completion
- 2026-12-31
- Completion
- 2026-12-31
- First posted
- 2023-10-27
- Last updated
- 2023-10-27
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT06105242. Inclusion in this directory is not an endorsement.