NCT06103526

Immunonutrition in ERAS Protocols in Gynecologic Oncology

Immunonutrition and Enhanced Recovery After Surgery Protocols in Gynecologic Oncology

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 200 (estimated)
• Sponsor: National and Kapodistrian University of Athens · Academic / Other
• Sex: Female
• Age: 20 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

A patient with oncological pathology of any type because of impaired digestion and nutrient absorption, decreased intake, and increased nutrition requirements has an increased risk of malnutrition and moderate to severe weight loss.In the present study the investigators will evaluate the impact of perioperative immunonutrition supplementation on the postoperative outcomes.

Detailed description

Malnutrition has a major effect not only on the postoperative course of cancer surgery but can also complicate or even limit administration or compromise the effectiveness of other treatments such as chemotherapy or radiotherapy in the perioperative period. Immunonutrition is a type of artificial nutrition based on the use of some types of macro- or micronutrients.The purpose of this review was to evaluate the use, indications, and effects of these formulas in oncologic surgical patients in real time and to identify the types of patients who can benefit from enteral immunonutrition.

Conditions

• Nutritional Deficiency
• Gynecologic Cancer
• ERAS

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Immunonutrition	enteral supplementation with high amount of proteins, arginine, glutamine, nonessential fatty acids, branched chain fatty acids, nucleotides, or RNA

Timeline

• Start date: 2023-10-18
• Primary completion: 2025-05-30
• Completion: 2025-08-30
• First posted: 2023-10-26
• Last updated: 2024-03-28

Locations

1 site across 1 country: Greece