Trials / Recruiting
RecruitingNCT06101862
Coronary Computed Tomography Versus Invasive Angiography for Non-ST Elevation Acute Coronary Syndrome
Team-based Interventional Triage in Acute Coronary Syndrome Based on Non-Invasive Computed Tomography Coronary Angiography - a Randomized Trial
- Status
- Recruiting
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 2,300 (estimated)
- Sponsor
- Rigshospitalet, Denmark · Academic / Other
- Sex
- All
- Age
- —
- Healthy volunteers
- Not accepted
Summary
Coronary computed tomography angiography (CCTA) is a widely accepted initial diagnostic test for individuals suspected of having chronic coronary syndromes. However, there is limited evidence supporting its use in the acute setting. So far, no large-scale randomized trial has examined the performance of CCTA as an alternative to invasive coronary angiography (ICA) in individuals with non-ST-segment elevation myocardial infarction (NSTEACS). If CCTA were to replace ICA as a routine procedure for individuals with NSTEACS, it could reduce the risk of complications related to ICA, improve patient comfort, expedite decision-making, and reduce healthcare expenses and interhospital transfers.
Conditions
- Ischemic Heart Disease
- Non STEMI
- Angina Pectoris, Unstable
- Coronary Disease
- Heart Attack
- Acute Myocardial Infarction (AMI)
- Randomized Controlled Trial
- Diagnostic Imaging
- Coronary Stenoses
- Coronary Artery Disease
- Multidetector Computed Tomography
- Percutaneous Coronary Intervention
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | CCTA | Participants will be examined with CCTA during admission. |
| PROCEDURE | Conventional ICA | Patients will be examined with conventional standard-of-care ICA. |
| OTHER | Team-based interventional triage | The CCTA will be discussed at a coronary CT-team conference to establish the treatment strategy and provide guidance for any necessary interventional procedure. |
Timeline
- Start date
- 2023-10-01
- Primary completion
- 2026-10-01
- Completion
- 2036-10-01
- First posted
- 2023-10-26
- Last updated
- 2025-02-19
Locations
6 sites across 1 country: Denmark
Source: ClinicalTrials.gov record NCT06101862. Inclusion in this directory is not an endorsement.