NCT06100263

Breast Cancer Resiliency Through Exercise Program (B-REP)

Breast Cancer Resiliency Through Exercise Program (B-REP): Pilot Study

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 75 (estimated)
• Sponsor: University of Michigan Rogel Cancer Center · Academic / Other
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The study will use a cross-sectional study design with a follow-up 2-arm randomized controlled trial with that has assessments at baseline, post-intervention (i.e., Week 12), and 3-months post-intervention (i.e., Week 24). The 2 arms are the 12-week intervention and waitlist control among 30 Black breast cancer survivors

Detailed description

14AUG2025- The sample size was updated, and the questionnaire was split into 2 questionnaires, as a planned solution in response to a low accrual 28OCT2025- Amendment was processed to update design and intervention items. The exercise threshold was changed from a 1-repeition maximum (1RM) to a 5-repeptition maximum (5RM). Since the intervention includes functional exercises, so we elected to use a functional strength (5RM) outcome rather than a maximal strength outcome (1RM) to better align with the intervention. The control condition was changed to a waitlist design. A waitlist control is more engaging, and there is a higher likelihood of retaining control participants.

Conditions

• Breast Cancer Female

Interventions

Type	Name	Description
OTHER	Individualized exercise program	guided exercise program for 12 weeks
OTHER	Control Arm	Control Arm Waiting List for 24 weeks, then offered a guided exercise program for 12 weeks

Timeline

• Start date: 2024-05-28
• Primary completion: 2026-12-01
• Completion: 2026-12-01
• First posted: 2023-10-25
• Last updated: 2026-02-10

Locations

1 site across 1 country: United States