Trials / Recruiting
RecruitingNCT06098495
Looking for a Blood Epigenetic Signature to Predict Female Infertility
- Status
- Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 1,456 (estimated)
- Sponsor
- Università Vita-Salute San Raffaele · Academic / Other
- Sex
- Female
- Age
- 18 Years – 43 Years
- Healthy volunteers
- Accepted
Summary
The present research project aims to study the DNAm mechanisms underlying the reduction of fertility due to the progressive depletion of oocyte quality. Specifically, our project aims to build an epigenetic clock for MGCs by using outcomes that are certainly related to female fertility. The validation of such findings will be carried out on peripheral blood in order to guarantee its non-invasiveness and allow for any clinical transferability. In order to identify a blood epigenetic signature able to predict female infertility, we planned to explore the problem from different points of view by conducting several studies in different settings.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| GENETIC | search for epigenetic profile of infertility | examine the epigenetic profile of DNA extracted from MGCs and blood sample |
Timeline
- Start date
- 2023-10-16
- Primary completion
- 2026-10-16
- Completion
- 2026-10-16
- First posted
- 2023-10-24
- Last updated
- 2023-10-24
Locations
1 site across 1 country: Italy
Source: ClinicalTrials.gov record NCT06098495. Inclusion in this directory is not an endorsement.