NCT06097104

Electrolytes Disturbances in Critically Ill Egyptian Patients

The Incidence, Risk Factors and Outcomes of Electrolytes Disturbances in Critically Ill Egyptian Patients: A Single-Centre Prospective Cohort Study

• Status: Enrolling By Invitation
• Phase: —
• Study type: Observational
• Enrollment: 110 (estimated)
• Sponsor: Ain Shams University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: —

Summary

All selected individuals will be subjected to the following: 1. Full medical history taking 2. Full clinical examination, APACHE II score on admission 3. Electrolytes panel daily on ICU admission 4. Estimate the duration of stay at ICU Also all selected individuals will be sectioned into groups regarding sites of collection (surgical ICU, CCU and medical ICU). All collected individuals will be sectioned regarding electrolytes imbalance into mild, moderate and severe groups

Detailed description

Study Procedures: All selected individuals will be suffering from electrolyte imbalance (EI) with the following data will be obtained: o Measurements: 1. Demographic data: age - gender - BMI - electrolytes data on ICU admission 2. Vital data: heart rate - respiratory rate - blood pressure measurement - Oxygen saturation - Urinary output - Temp +/- CVP measurement. 3. Lab.: "CBC - Kidney function tests - liver function tests - ABG - levels of serum sodium, potassium, magnesium, phosphorus, ionized calcium and chloride", with maximum 5 mm blood sampling per day. Serum-sodium levels will be corrected for serum-glucose by lowering the sodium concentration by 2.4 mmol/L for every 100 mg/dl increase in glucose. Corrected Sodium = Measured sodium + 0.016 (Serum glucose - 100) A correction formula was also used to calculate albumin-corrected calcium levels (mmol/L) Corrected Calcium = (0.8 (Normal Albumin - Pt's Albumin)) + Serum Ca 4. APACHE II score 5. Comorbidities 6. Complications: AKI- Acute myocardial infarction 7. Duration of ICU stay 8. Duration of hospital stay 9. Outcome (regarding eventual complications: AKI- Acute myocardial infarction)

Conditions

• Electrolyte Imbalance

Interventions

Type	Name	Description
OTHER	electrolytes - serum blood samples	CBC - Kidney function tests - liver function tests - ABG - levels of serum sodium, potassium, magnesium, phosphorus, ionized calcium and chloride", with maximum 5 mm blood sampling per day

Timeline

• Start date: 2023-09-26
• Primary completion: 2024-08-08
• Completion: 2024-08-08
• First posted: 2023-10-24
• Last updated: 2024-08-05

Locations

1 site across 1 country: Egypt