NCT06095635

Acute Influence of Resveratrol Supplementation and Beet Extract in Recovery After Exercise in Coronary Paths

Acute Influence of Resveratrol Supplementation and Beet Extract in Recovery After Exercise Submaximal Aerobic in Coronary Paths: a Study Prospective, Randomized Placebo-controlled

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 17 (actual)
• Sponsor: Universidade Estadual Paulista Júlio de Mesquita Filho · Academic / Other
• Sex: Male
• Age: 40 Years – 79 Years
• Healthy volunteers: Not accepted

Summary

Introduction: Most cardiovascular diseases (CVD) can be prevented and controlled by adopting lifestyle changes, such as regular physical exercise and nutrition. Resveratrol and beverage extract promote beneficial health effects due to their nutritional properties. Objective: to analyze the effects of resveratrol supplementation and withdrawal extract on post-exercise recovery in coronary heart disease patients. Methods: men diagnosed with ischemic coronary artery disease will undergo four exercise protocols consisting of 30 minutes of aerobic exercise on an ergometric treadmill, with 5 minutes of warm-up, intensity of 30% of the heart rate reserve (HRR), followed by 25 minutes at intensity 60% of FCR and for a final 30 minutes of recovery in the supine position. Before each exercise protocol, all volunteers will consume: 500 mg of placebo (starch), or 500 mg of beetroot, or 500 mg of resveratrol and will also consume resveratrol and drink (500 mg each) 30 minutes before exercise. , the order of each supplementation will be done randomly. Cardiorespiratory parameters and heart rate variability (HRV) will be assessed at different times throughout the experimental procedure. To analyze the moments (rest versus recovery), the Bonferroni post-test will be used for parametric distribution or the Dunn post-test for non-parametric distribution. Statistical significance will be calculated at 5% for all analyses.

Conditions

• Coronary Artery Disease
• Autonomic Nervous System Disease
• Blood Pressure
• Heart Rate

Interventions

Type	Name	Description
OTHER	Placebo Protocol	ingestion of 500 mg of starch following 30 minutes of exercise (treadmill)
OTHER	Protocol Beet	ingestion of 500 mg of beet extect following 30 minutes of exercise (treadmill)
OTHER	Protocol Resveratrol	ingestion of 500 mg of resveratrol following 30 minutes of exercise (treadmill)
OTHER	Protocol Beet and Resveratrol	ingestion 500 mg of beet extect and 500 mg of resveratrol following 30 minutes of exercise (treadmill)

Timeline

• Start date: 2022-03-10
• Primary completion: 2023-01-10
• Completion: 2023-09-30
• First posted: 2023-10-23
• Last updated: 2023-10-23

Locations

1 site across 1 country: Brazil