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UnknownNCT06094530

18F-FAPI-RGD PET/CT in Various Tumor Types

Clinical Evaluation of 18F-FAPI-RGD PET/CT for Imaging of Fibroblast Activation Protein and Integrin avb3 in Various Tumor Types

Status
Unknown
Phase
Study type
Observational
Enrollment
100 (estimated)
Sponsor
Sichuan Provincial People's Hospital · Academic / Other
Sex
All
Age
10 Years – 80 Years
Healthy volunteers
Accepted

Summary

The clinical feasibility of 18F-FAPI-RGD PET/CT will be evaluated in 100 patients with various types of tumor, and the results will be compared with those of 18F-FDG.

Detailed description

The aim of this study is to evaluate, in patients with various types of tumor, the radiotracer uptake and clinical feasibility of 18F-FAPI-RGD PET/CT compared with those of 18F-FDG PET/CT. To evaluate the diagnostic performance of 18F-FAPI-RGD and 18F-FDG PET imaging, the results of the visually interpreted PET images will be compared with the histopathologic results (via surgery or biopsy), which are used as the gold standard for the final diagnosis. For patients for whom tissue diagnosis is not applicable, clinical and radiographic follow-up data will be used as the reference standard to validate the PET/CT findings.

Conditions

Timeline

Start date
2023-04-10
Primary completion
2024-09-01
Completion
2024-10-01
First posted
2023-10-23
Last updated
2023-10-23

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT06094530. Inclusion in this directory is not an endorsement.

18F-FAPI-RGD PET/CT in Various Tumor Types (NCT06094530) · Clinical Trials Directory