NCT06094504

Spectral Lighting and Intestinal Failure

Impact of Full Spectrum Light on Outcomes of Infants With Intestinal Failure

• Status: Enrolling By Invitation
• Phase: N/A
• Study type: Interventional
• Enrollment: 32 (estimated)
• Sponsor: Children's Hospital Medical Center, Cincinnati · Academic / Other
• Sex: All
• Age: 1 Year
• Healthy volunteers: Not accepted

Summary

The goal of this exploratory n-of-1-study is to compare markers of metabolism in infants with intestinal failure between two lighting environments. Investigators are seeking to learn whether supplementing the lighting environment of infants with intestinal failure with blue and violet wavelengths of light will allow more efficient utilization of the nutrition provided to participants by influencing hormones involved in regulation of growth and development as compared to a conventional lighting environment. Pre-clinical studies suggest that violet and blue wavelengths of light are involved in molecular pathways that help regulate metabolic activity.

Conditions

• Intestinal Failure

Interventions

Type	Name	Description
OTHER	Spectral Lighting	Spectral room lighting containing violet and blue wavelengths of light capable of stimulating non-visual opsins including OPN5 and OPN3.

Timeline

• Start date: 2024-03-01
• Primary completion: 2026-09-15
• Completion: 2027-03-15
• First posted: 2023-10-23
• Last updated: 2024-12-16

Locations

1 site across 1 country: United States