Trials / Completed
CompletedNCT06093945
Effect of Omeprazole on Pharmacokinetics of SHR2554 in Healthy Subjects
Study to Evaluate the Drug-drug Interaction Effect of Omeprazole on the Pharmacokinetics of SHR2554 in Healthy Subjects: A Single-center, Open-label, Single-dose, Two-period, Fixed Sequence, Self-controlled Study
- Status
- Completed
- Phase
- Phase 1
- Study type
- Interventional
- Enrollment
- 20 (actual)
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd. · Industry
- Sex
- All
- Age
- 18 Years – 45 Years
- Healthy volunteers
- Accepted
Summary
The study aimed to assess the effects of omeprazole on single-dose SHR2554 in healthy subjects, exploring the pharmacokinetic changes of SHR2554 and ensuring the safety when SHR2554 is co-administered with omeprazole.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | SHR2554 tablet dosing | SHR2554 350mg taken on Day 1 and Day 10 |
| DRUG | Omeprazole tablet dosing | Omeprazole taken from Days 5 to Day 10 |
Timeline
- Start date
- 2023-11-06
- Primary completion
- 2023-11-29
- Completion
- 2023-11-29
- First posted
- 2023-10-23
- Last updated
- 2023-12-05
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT06093945. Inclusion in this directory is not an endorsement.