NCT06091982

Renal Replacement Therapy and In-Hospital Mortality Incidence in Cardiac Surgery Associated Acute Kidney Injury

The Need of Renal Replacement Therapy and In-Hospital Mortality Incidence In Patients With Cardiac Surgery Associated Acute Kidney Injury: Retrospective Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 1,113 (actual)
• Sponsor: National Cardiovascular Center Harapan Kita Hospital Indonesia · Academic / Other
• Sex: All
• Age: 18 Years – 85 Years
• Healthy volunteers: Not accepted

Summary

The goal of this study is to analyse the relation of severe acute kidney injury post cardiac surgery which characterised by the need of renal replacement therapy, with in-hospital postoperative mortality incidence. The main question it aims to answer: To compare between patients complicated with acute kidney injury and exposure of renal replacement therapy (AKI-RRT) and patients complicated with acute kidney injury which does not require renal replacement therapy, in associated with in-hospital postoperative mortality.

Detailed description

Type of study: observational study Participant population: Post cardiac surgery patients with condition of acute kidney injury postoperative, will be assigned into 2 groups, based on their exposure to renal replacement therapy. Those groups are: Group AKI-RRT : patients with AKI postoperative with exposure of renal replacement therapy Group AKI non RRT : patients with AKI postoperative, with no exposure to renal replacement therapy Researchers will compare group AKI-RRT and AKI non RRT to analyse the association to postoperative mortality, and other factors that related to mortality variable.

Conditions

• Acute Kidney Injury

Interventions

Type	Name	Description
PROCEDURE	Renal Replacement Therapy (RRT)	Renal Support therapy which consist of procedure of intermittent hemodialysis (IHD) or continuous veno-venous hemofiltration/hemodialysis/hemodiafiltration (CVVH/CVVHD/CVVHDF)

Timeline

• Start date: 2023-10-01
• Primary completion: 2024-06-30
• Completion: 2024-06-30
• First posted: 2023-10-23
• Last updated: 2024-10-17
• Results posted: 2024-10-17

Locations

1 site across 1 country: Indonesia