NCT06090526

PSP as Indicator for Urinary Sepsis in ICU

Pancreatic Stone Protein as Indicator for Urinary Sepsis in Intensive Care Units

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 80 (estimated)
• Sponsor: Ain Shams University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. For clinical operationalization, organ dysfunction can be represented by an increase in the Sequential Organ Failure Assessment (SOFA) score of 2 points or more, which is associated with an in-hospital mortality greater than 10%. pancreatic stone protein has been studied as biomarker of sepsis and results suggests that it has higher diagnostic performance. The main objective of this study is to identify ability of pancreatic stone protein (PSP) as a new biomarker for diagnosis of urosepsis in Intensive Care Units comparison to other biomarkers and its role as a prognostic marker for mortality

Conditions

• Urinary; Sepsis

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	pancreatic stone protein "PSP" measurement	Blood samples will be collected for biomarker (PCT, CRP, and PSP) measurements in admission and 24 hours, 72 hours from admission and patients will be followed until death or discharge from the ICU or for 30 days, whichever occurred.

Timeline

• Start date: 2024-05-01
• Primary completion: 2024-12-31
• Completion: 2025-03-31
• First posted: 2023-10-19
• Last updated: 2023-10-19