NCT06086795

Investigating Age-dependent Effects of Egg Intake on HDL and Immune Profiles

• Status: Active Not Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 46 (estimated)
• Sponsor: University of Connecticut · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Accepted

Summary

The goal of this intervention study is to determine whether consumption of different fractions of chicken eggs, including egg whites, egg yolks, and whole eggs, confer different changes in markers of HDL function and T cell profiles in younger vs. older men and women. The study will address the following objectives: * Objective 1: Determine if daily consumption of egg fractions differentially alter HDL profiles across age groups. * Objective 2: Determine if daily consumption of egg fractions differentially alter immune cell profiles across age groups. Participants will be asked to consume egg whites, egg yolks, and whole eggs on a daily basis for 4-weeks each, and avoid eating eggs for a total of 8 weeks at different points in the study. Participants will additionally be provided guidance on following a generally healthy diet, and will be asked to complete surveys about dietary intake and physical activity, as well as provide blood samples throughout the course of the study. Researchers will compare whether daily consumption of egg whites, egg yolks, and whole eggs differentially alter markers of HDL function and T cell profiles in younger vs. older adults.

Conditions

• Lipoproteins
• Inflammatory Response

Interventions

Type	Name	Description
OTHER	Whole eggs	3 large whole eggs per day for 4 weeks
OTHER	Egg yolks	3 large egg equivalent of egg yolks per day for 4 weeks
OTHER	Egg whites	3 large egg equivalent of egg whites per day for 4 weeks

Timeline

• Start date: 2024-01-23
• Primary completion: 2026-06-01
• Completion: 2026-06-01
• First posted: 2023-10-17
• Last updated: 2025-08-05

Locations

1 site across 1 country: United States