NCT06086769

High Flow Oxygen Therapy Effect on Healthy Subjects

Impact of High Flow Oxygen Therapy on Diaphragm Thickening Fraction in Healthy Subjects. A Prospective Cohort Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 13 (actual)
• Sponsor: Argentinian Intensive Care Society · Academic / Other
• Sex: All
• Age: 18 Years – 35 Years
• Healthy volunteers: Accepted

Summary

The use of high-flow nasal cannula (HFNC) has increased. Diaphragmatic ultrasonography is a tool that, as a noninvasive complement to esophageal pressure (Pes) measurement, allows the evaluation of diaphragm function and reflects, through the diaphragm thickening fraction (DTf), the magnitude of diaphragmatic fiber recruitment. The objective of this study was to evaluate the impact of HFNC therapy on the DTf in healthy subjects. Second, this study aimed to assess the behavior of the respiratory rate (RR) and the work of breathing in these subjects.

Conditions

• Healthy Volunteers
• Diaphragm
• Respiratory Rate

Interventions

Type	Name	Description
DEVICE	High flow nasal canula	Measurement of diaphragm thickening fraction, respiratory rate and esophageal pressure swing with calculation of diaphragmatic pressure-time product without the use of HFNC and with the use of HFNC at 20 and 40 Liters per minute

Timeline

• Start date: 2022-03-01
• Primary completion: 2022-05-30
• Completion: 2022-06-30
• First posted: 2023-10-17
• Last updated: 2023-10-17

Locations

1 site across 1 country: Argentina