NCT06084507

Food Effects of GST-HG171 Tablets Combined With Ritonavir in Healthy Chinese Participants

Food Effects Study of GST-HG171 Tablets Combined With Ritonavir in Healthy Chinese Participants

• Status: Unknown
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 18 (estimated)
• Sponsor: Fujian Akeylink Biotechnology Co., Ltd. · Industry
• Sex: All
• Age: 18 Years – 50 Years
• Healthy volunteers: Accepted

Summary

A single-center, randomized, open, single-dose, two-cycle, two-sequence, cross-over study was conducted to evaluate the effect of food on the pharmacokinetic characteristics of GST-HG171 in combination with Ritonavir.

Conditions

• COVID-19 Respiratory Infection

Interventions

Type	Name	Description
DRUG	GST-HG171/ritonavir	Single oral dose of GST-HG171 300 mg (2 × 150 mg tablets)/ritonavir 100 mg under fed or fasted conditions at 0 hour on Day 1
DRUG	ritonavir	Single oral dose of ritonavir 100 mg at -12 hours prior to GST-HG171/ritonavir dosing, and ritonavir 100 mg will be dosed at 12 hours and 24 hours after GST-HG171/ritonavir dosing.

Timeline

• Start date: 2023-05-04
• Primary completion: 2023-05-23
• Completion: 2023-12-27
• First posted: 2023-10-16
• Last updated: 2023-10-16

Locations

1 site across 1 country: China