NCT06082076

Prevention of Shivering Associated With Spinal Anesthesia

Dexmedetomidine Versus Ketamine to Prevent Shivering Associated With Intrathecal Anesthesia in Patients Undergoing Knee Arthroscopy:A Randomized, Controlled Double Blinded Study.

• Status: Unknown
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 90 (estimated)
• Sponsor: Assiut University · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Accepted

Summary

The aim of the study is to compare the effectiveness of prophylactic use of intravenous (IV) dexmedetomidine VS ketamine and meperidine(as a control group) in prevention of shivering associated with intrathecal anesthesia in patients undergoing knee arthroscopy

Conditions

• Shivering, Spinal Anesthesia

Interventions

Type	Name	Description
DRUG	Dexmedetomidine	Patients will receive dexmedetomidine 0.5 mcg/kg diluted in 10 mL of NS given as IV infusion over 10 min before induction of spinal anesthesia
DRUG	Ketamine	Patient will will receive ketamine 0.5 mg/kg diluted in 10 mL of NS given as IV infusion over 10 min before induction of spinal anesthesia
DRUG	Meperidine	If the tested drug hasn't stopped shivering patient will receive 0.25 mg/kg meperidine

Timeline

• Start date: 2023-11-01
• Primary completion: 2024-11-01
• Completion: 2024-12-01
• First posted: 2023-10-13
• Last updated: 2023-10-13