NCT06081738

Neostigmine Versus Sugammadex on Renal Functions

Evaluation of The Effects of Neostigmine Versus Sugammadex on Renal Functions in Laparoscopic Cholecystecomy A Randomized Controlled Study

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 64 (actual)
• Sponsor: Menoufia University · Academic / Other
• Sex: All
• Age: 20 Years – 55 Years
• Healthy volunteers: Accepted

Summary

The study will assess the acute effects of sugammadex or neostigmine on renal function as determined with more specific and sensitive tests in laparoscopic cholecystectomy

Conditions

• Sugammadex
• Neostigmine

Interventions

Type	Name	Description
DRUG	Neostigmine	a combination of 0.04 mg/kg neostigmine with 0.01 mg/kg atropine intravenously at the reappearance of a second twitch of TOF after the last dose of rocuronium
DRUG	Sugammadex	2-4 mg/kg sugammadex intravenously upon the reappearance of a post-tetanic count 1-2 or a second twitch of TOF after the last dose of rocuronium

Timeline

• Start date: 2023-03-01
• Primary completion: 2023-09-01
• Completion: 2023-12-31
• First posted: 2023-10-13
• Last updated: 2023-10-13

Locations

1 site across 1 country: Egypt