Clinical Trials Directory

Trials / Completed

CompletedNCT06081621

A Clinical Study to Evaluate the Efficacy and Safety of REGEND001 Cell Therapy on Idiopathic Pulmonary Fibrosis (IPF)

A Multi-center, Randomized, Double-Blinded, Parallel and Placebo-Controlled Phase II Clinical Study to Evaluate the Efficacy and Safety of REGEND001 Cell Therapy in Idiopathic Pulmonary Fibrosis (IPF) Patients

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
23 (actual)
Sponsor
Regend Therapeutics · Industry
Sex
All
Age
40 Years – 75 Years
Healthy volunteers
Not accepted

Summary

Idiopathic pulmonary fibrosis (IPF) is a serious chronic (long term) disease with injury of lung tissues. REGEND001 is a cell therapy product, made from bronchial basal cells with ability to regenerate lung tissue, is promising to IPF treatment. This is a multi-center, randomized, double-blinded, parallel and placebo-controlled phase II clinical study to evaluate the efficacy and safety of REGEND001 in IPF patients.

Conditions

Interventions

TypeNameDescription
BIOLOGICALREGEND001REGEND001: 1-1.5×10\^6 bronchial basal cells/kg administrated by bronchoscopy.
BIOLOGICALPlaceboPlacebo: Sodium chloride injection administrated by bronchoscopy.

Timeline

Start date
2023-12-11
Primary completion
2025-03-14
Completion
2025-03-14
First posted
2023-10-13
Last updated
2026-03-18

Locations

4 sites across 1 country: China

Source: ClinicalTrials.gov record NCT06081621. Inclusion in this directory is not an endorsement.