NCT06077604

Influence of Air Pollution on SPondyloarthritis Flare-ups and Resistance to Treatment

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 182 (actual)
• Sponsor: Centre Hospitalier Universitaire de Besancon · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The relationship between exposure to air pollution and spondyloarthritis (SpA) has been poorly studied. Based on data from the literature on other inflammatory pathologies such as rheumatoid arthritis, we hypothesize that there is a relationship between exposure to air pollution and the risk of presenting a flare-up in SpA patients following and living in Franche-Comté (France). Primary objective:The potential relationship between exposure to air pollution (nitrogen dioxide, fine particles with a diameter of less than 10 or 2.5 microns and Ozone) and the onset of a spondyloarthritis flare-up will be explored in patients with this pathology.

Conditions

• Spondyloarthritis, Axial

Interventions

Type	Name	Description
OTHER	Assessment of exposure to air pollution	For each patient, exposure to air pollution will be assessed over a period immediately prior to any flare-up and over four periods at a distance from the flare-up.

Timeline

• Start date: 2024-03-01
• Primary completion: 2024-10-15
• Completion: 2024-10-15
• First posted: 2023-10-11
• Last updated: 2025-07-09

Locations

1 site across 1 country: France