NCT06075693

Cerebrospinal Fluid Biomarkers of Myotonic Dystrophy

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 88 (estimated)
• Sponsor: Massachusetts General Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: —

Summary

Myotonic dystrophy is associated with central sleep apnea, excessive daytime sleepiness, diminished working memory, impaired visuospatial skills, and deficits in problem-solving skills. Cerebrospinal fluid (CSF) is a clear, colorless fluid that surrounds and protects the brain. Changes in the composition of CSF can serve as early indicators of changes in brain activity and function. The purpose of this research is to learn about myotonic dystrophy by examining cerebrospinal fluid and brain activity in participants. The tests will be low risk and are well tolerated. The information that we gather from this study may help us evaluate, prevent, diagnose, treat, and improve our understanding of myotonic dystrophy. Funding Source- FDA OOPD

Conditions

• Myotonic Dystrophy Type 1

Timeline

• Start date: 2022-08-01
• Primary completion: 2027-08-01
• Completion: 2028-08-01
• First posted: 2023-10-10
• Last updated: 2025-11-24

Locations

1 site across 1 country: United States