NCT06075134

EMG-guided Botox Injection Versus Conventional Botox Injection in Gummy Smile Patients

EMG-guided Botox Injection Versus Conventional Injection in Yonsei Point in Gummy Smile Patients: A Randomized Clinical Trial

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 32 (estimated)
• Sponsor: Cairo University · Academic / Other
• Sex: All
• Age: 18 Years – 50 Years
• Healthy volunteers: Accepted

Summary

The goal of this clinical trial is to compare the effect of EMG-guided Botox injection with conventional Botox injection in Yonsei point, in patients with excessive gingival display. The main question it aims to answer is: • Does the use of electromyography (EMG) as a guide during Botox injection for patients with gummy smile has better effect than conventional injection in Yonsei point? Participants will be randomized in equal proportions between intervention and control groups. * Preoperative assessment of amount of gingival display, lip length (philtrum and vermilion length), and smile type. * For the intervention group, EMG readings will be done in Clinical Neurophysiology Department, Kasr Al-Ainy Hospital EMG-guided Botox injection (Intervention group). Conventional Botox injection in Yonsei point (Control group).

Conditions

• Excessive Gingival Display

Interventions

Type	Name	Description
PROCEDURE	Botox injection	Botox injection
DEVICE	EMG	Quantitative Electromyography
DRUG	Zinc Supplement	To increase efficacy of Botox

Timeline

• Start date: 2024-11-01
• Primary completion: 2026-06-01
• Completion: 2026-08-01
• First posted: 2023-10-10
• Last updated: 2026-03-20

Locations

1 site across 1 country: Egypt