NCT06073951

Evaluation of a Couple-Based Physical Activity Intervention

Mates in Motion: Feasibility and Acceptability of a Couple-Based Physical Activity Intervention

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 96 (actual)
• Sponsor: Mayo Clinic · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

This clinical trial tests how well a couple-based physical activity (PA) intervention, Mates in Motion, works in patients undergoing hematopoietic cell transplantation (HCT) or chimeric antigen receptor T-cell therapy (CART) and their care giving partners to be more physically active. Mates in Motion provides training in communication skills and behavior change techniques to help HCT patient-caregiver dyads support one another in adoption and maintenance of PA. This study may help researchers determine if a couple-based PA intervention improves PA, physical endurance and global physical health among patient-care giver dyads undergoing HCT or CART.

Detailed description

PRIMARY OBJECTIVES: I. To determine feasibility of recruitment, adherence, and retention of a couple-based PA intervention in a pilot randomized controlled trial (RCT). II. Determine acceptability of the intervention (multiple dimensions of treatment satisfaction). III. Describe changes in PA, physical endurance, and global physical health from baseline to follow-up as a function of randomized condition. OUTLINE: Patient-caregiver dyads are randomized to 1 of 2 arms. ARM I: Dyads participate in the Mates in Motion program consisting of weekly sessions to train couples in the use of communal coping strategies to support one another in achieving PA goals and skill building focus on instruction and practice in effective communication, with emphases on adaptive speaking, responsive listening, and joint decision-making and problem-solving around PA over 8 weeks. Patient-partner dyads receive weekly step-count goals, complete walk-tests and questionnaires and wear an Actigraph device and Garmin activity tracker on study. ARM II: Patient-partner dyads wear an Actigraph device, compete walk-tests and questionnaires on study. Dyads receive usual care on study. Dyads receive a Garmin activity tracker at the end of the study.

Conditions

• Hematopoietic and Lymphoid System Neoplasm
• Malignant Solid Neoplasm

Interventions

Type	Name	Description
OTHER	Best Practice	Receive usual care
OTHER	Exercise Counseling	Receive walking step goals
OTHER	Exercise Intervention	Participate in Mates in Motion program
OTHER	Medical Device Usage and Evaluation	Wear Actigraph
OTHER	Medical Device Usage and Evaluation	Wear Garmin activity tracker
OTHER	Physical Performance Testing	Undergo walk-test
OTHER	Questionnaire Administration	Complete questionnaires

Timeline

• Start date: 2024-03-11
• Primary completion: 2025-09-03
• Completion: 2025-09-03
• First posted: 2023-10-10
• Last updated: 2025-09-24

Locations

1 site across 1 country: United States