NCT06073704

Effects of Adjunct Antimicrobial Photodynamic Therapy in Periodontal Treatment of Patients with Obesity

Effects of Antimicrobial Photodynamic Therapy in Non-surgical Periodontal Treatment of Patients with Obesity

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 24 (estimated)
• Sponsor: University of Sao Paulo · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

The goal of this clinical trial is to compare the effects of adjuvant antimicrobial photodynamic therapy (aPDT) as an adjuvant of scaling and root planing with scaling and root planing alone for periodontal treatment in patients with periodontal disease and obesity. The main question it aims to answer are: Does adjuvant aPDT improves periodontal health? Are there differences in the proteomic profile of gingival fluid after both treatments? Participants will receive scaling and root planing complemented or not by aPDT. Results will be collected after 1, 3, and 6 months. Researchers will compare adjuvant aPDT treatment to regular treatment to see if it promotes reduction in inflammation and improvement in periodontal health.

Conditions

• Periodontitis
• Obesity

Interventions

Type	Name	Description
PROCEDURE	antimicrobial photodynamic therapy (aPDT)	Scaling and root planing followed by antimicrobial photodynamic therapy
PROCEDURE	Control	Treatment of scaling and root planing

Timeline

• Start date: 2023-10-09
• Primary completion: 2025-04-30
• Completion: 2025-06-30
• First posted: 2023-10-10
• Last updated: 2024-12-05

Locations

1 site across 1 country: Brazil