Trials / Unknown
UnknownNCT06073015
Effect of Esketamine on Reducing Postoperative Anxiety and Depression in Adolescent Patients
- Status
- Unknown
- Phase
- EARLY_Phase 1
- Study type
- Interventional
- Enrollment
- 200 (estimated)
- Sponsor
- Henan Provincial People's Hospital · Academic / Other
- Sex
- All
- Age
- 8 Years – 18 Years
- Healthy volunteers
- Accepted
Summary
This study intends to conduct a prospective, double-blind, randomized, controlled trial. Adolescents aged 8-17 years old are selected as subjects. Esketamine is used as intervention before surgery, vital signs data, serum IL-6, CRP and other inflammatory indicators are collected during surgery, and the incidence and degree of anxiety and depression are evaluated after surgery. To determine the effect of esketamine on reducing anxiety and depression in adolescents after surgery, and to provide an effective clinical basis for accelerating the rehabilitation of adolescents after surgery.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Esketamine | Group S received a subanesthetic dose of esketamine 0.2mg/kg (2ml/50 mg) 5 minutes before the procedure began. |
Timeline
- Start date
- 2023-10-10
- Primary completion
- 2024-12-10
- Completion
- 2025-02-10
- First posted
- 2023-10-10
- Last updated
- 2023-10-10
Source: ClinicalTrials.gov record NCT06073015. Inclusion in this directory is not an endorsement.