NCT06070480

Effects of Different Types of Anaesthesia on Intraocular Pressure During Lumbar Disc Herniation Surgery

Effects of Propofol, Desflurane and Spinal Anesthesia on Intraocular Pressure During Lumbar Disc Herniation Surgery: A Randomized Controlled Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 75 (actual)
• Sponsor: Giresun University · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

The aim of this study was to investigate the effects of anaesthesia methods on intraocular pressure during lumbar disc surgery performed in the prone position.

Detailed description

The study included 75 patients with lumbar disc herniation between the ages of 18-75, with the American Society of Anesthesiologists (ASA) 1-2. The patients were randomly divided into 3 groups: propofol, desflurane, spinal. Intraocular pressure (IOP) was measured at 5 time points throughout surgery, including baseline (T1), 10 minutes after anesthesia (T2), 10 minutes after prone positioning (T3: early prone), 30 minutes after prone positioning (T4: late prone), and 10 minutes after returning to the supine position (T5). Hemodynamic parameters were measured at these time points. Hemoglobin and hematocrit values were measured preoperatively and on the first postoperative day.

Conditions

• Anesthesia
• Disk Herniated Lumbar
• Intraocular Pressure

Interventions

Type	Name	Description
OTHER	Spinal Anesthesia Group	Effect of spinal anesthesia on intraocular pressure
OTHER	Desflurane Group	Effect of general anesthesia with desflurane on intraocular pressure
OTHER	Propofol Group	Effect of general anesthesia with propofol on intraocular pressure

Timeline

• Start date: 2022-01-05
• Primary completion: 2023-01-02
• Completion: 2023-05-15
• First posted: 2023-10-06
• Last updated: 2023-10-06

Locations

1 site across 1 country: Turkey (Türkiye)