Trials / Unknown
UnknownNCT06068205
COMPARATIVE ANALYSIS OF THE MORPHO-MECHANICAL PROPERTIES OF RED BLOOD CELLS EXTRACTED FROM DIABETIC PATIENTS WITH AND WITHOUT MICROVASCULAR COMPLICATIONS
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 48 (estimated)
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Academic / Other
- Sex
- All
- Age
- 50 Years – 70 Years
- Healthy volunteers
- Not accepted
Summary
The aim of the study is to analyse the biomechanical stiffness of red blood cells extracted from subjects with type I diabetes with and without microvascular complications through a biophysical characterization of red blood cells using microscopy, spectroscopy and scattering measurements. 48 subjects with type 1 diabetes, 24 with and 24 without microvascular complications will be enrolled. From all subjects a single blood sample will be taken to perform the analysis of red blood cells morpho-mechanical properties.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIAGNOSTIC_TEST | Blood test - atomic force microscopy in the force spectroscopy mode | A single blood test to be analysed through atomic force microscopy in the force spectroscopy mode |
Timeline
- Start date
- 2023-09-29
- Primary completion
- 2025-07-29
- Completion
- 2025-09-29
- First posted
- 2023-10-05
- Last updated
- 2023-10-05
Source: ClinicalTrials.gov record NCT06068205. Inclusion in this directory is not an endorsement.