NCT06067932

Foot Disorders in X-linked Hypophosphatemia

Mid- and Forefoot Disorders in Adolescents and Adults With X-linked Hypophosphatemia

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 28 (actual)
• Sponsor: Orthopedic Hospital Vienna Speising · Academic / Other
• Sex: All
• Age: 16 Years – 100 Years
• Healthy volunteers: Not accepted

Summary

This study aimed to characterize foot pathologies using X-rays and clinical examination and assess related outcome scores in adolescents and adults with X-linked Hypophophatemia

Detailed description

A single center, cross-sectional analysis of adolescent and adult patients with XLH with and without previous surgical intervention was performed at the Orthopaedic Hospital Speising, Vienna, Austria. Clinical examination, quality of life questionnaires and radiographic data of foot x-rays in standing position were collected. Radiographic evaluation was performed to analyze foot deformity as well as signs of osteoarthritis at the foot.

Conditions

• X-linked Hypophosphatemia

Interventions

Type	Name	Description
RADIATION	Foot X rays	Radiographs of ankle and foot anteroposterior/dorsoplantar were taken in standing position with a centralized beam on the ankle joint.
DIAGNOSTIC_TEST	Clinical examination + scores	The American Orthopedic Foot and Ankle Society Score (AOFAS- midfoot section and 1st Forefoot ray, Forefoot ray 2-5) and the foot function index (FFI) were assessed

Timeline

• Start date: 2020-07-01
• Primary completion: 2021-07-01
• Completion: 2021-07-01
• First posted: 2023-10-05
• Last updated: 2023-10-10

Locations

1 site across 1 country: Austria