NCT06067217

Comparative Study of Tranexamic Acid, Estrogen for Treatment AUB in DMPA Users

Comparative Study of Tranexamic Acid, Estrogen for Treatment Abnormal Uterine Bleeding in Depot-medroxyprogesterone Acetate Users. A Randomized Controlled Trial

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 52 (estimated)
• Sponsor: Department of Medical Services Ministry of Public Health of Thailand · Other Government
• Sex: Female
• Age: 18 Years – 45 Years
• Healthy volunteers: Accepted

Summary

Abnormal uterine bleeding is the most common problems to discontinue Depo-medroxyprogesterone acetate (DMPA) in Thailand. This clinical trial use to provide drug to stop abnormal uterine bleeding from DMPA

Detailed description

Abnormal uterine bleeding is the most common problems to discontinue Depo-medroxyprogesterone acetate (DMPA) in Thailand. After discontinue DMPA, patients have not used any method. Unwanted pregnancy are rising. The reason of abnormal uterine bleeding from DMPA aren't clearly understand. In present, no standard treatment to treat abnormal utrerine bleeding in DMPA users.This clinical trial use to provide drug to stop abnormal uterine bleeding from DMPA with minimal dose and minimal side effect

Conditions

• Abnormal Uterine Bleeding
• Tranexamic Acid
• Estrogen
• Depot Medroxyprogesterone Acetate

Interventions

Type	Name	Description
DRUG	Tranexamic acid 250 mg oral tablet	Compare between tranexamic acid and progynova to stop abnormal uterine bleeding in DMPA users
DRUG	Progynova 1 mg oral tablet	Compare between tranexamic acid and progynova to stop abnormal uterine bleeding in DMPA users

Timeline

• Start date: 2023-09-30
• Primary completion: 2024-08-01
• Completion: 2024-08-30
• First posted: 2023-10-04
• Last updated: 2023-11-18

Locations

2 sites across 1 country: Thailand