NCT06065267

Levofloxacin Concomitant Versus Levofloxacin Sequential

Efficacy of Two-week Therapy With Levofloxacin-based Concomitant Regimen Versus Levofloxacin-based Sequential Regimen for Helicobacter Pylori Infection in Syrian Population: a Prospective Single-center Randomized Controlled Trial

• Status: Not Yet Recruiting
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 150 (estimated)
• Sponsor: Damascus Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

The goal of this trial is to determine the efficacy of levofloxacin based sequential treatment regimen or concomitant levofloxacin based regimens as empirical first-line therapy in the Syrian population

Conditions

• Helicobacter Pylori Infection

Interventions

Type	Name	Description
DRUG	sequential	amoxicillin 1000 mg bid ,esomprazole 20 bid for one week then levofloxacine 500 mg q.d, metraonidazoel 500 500 bid, and esomprazole 20 bid for one week
DRUG	Levofloxacin 500Mg Oral Tablet	Levofloxacin 500 mg qd, amoxicillin 500 2cab bid,Tinadizole 500 bid, esomprazole 20 bid

Timeline

• Start date: 2024-01-02
• Primary completion: 2026-12-31
• Completion: 2027-06-30
• First posted: 2023-10-03
• Last updated: 2023-10-03

Locations

1 site across 1 country: Syria